Evidence map›Paper›PMID 41079364›Full record

ArticleFrontiers in neurology2025

Effects of Chinese cervical fixed-point rotation manipulation on heart rate variability in patients with sympathetic cervical spondylosis based on the theory of biomechanical equilibrium: a study protocol for a randomized controlled trial.

Xiayang Zeng, Shengming Zheng, Yunxing Xie, Hongyi Ma, Jinhong Zuo, Zhenyu Fan, Pengfei Qiu

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiayang ZengDepartment of Tui Na, Zhejiang Hospital, Hangzhou, China.
Shengming ZhengDepartment of Tui Na, Zhejiang Hospital, Hangzhou, China.
Yunxing XieDepartment of Tui Na, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Hongyi MaDepartment of Tui Na, Zhejiang Hospital, Hangzhou, China.
Jinhong ZuoDepartment of Tui Na, Zhejiang Hospital, Hangzhou, China.
Zhenyu FanDepartment of Tui Na, Zhejiang Hospital, Hangzhou, China.
Pengfei QiuDepartment of Acupuncture and Moxibustion, Zhejiang Hospital, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As a complex cervical spondylosis with symptoms involving multiple systems and organs, SCS is easily misdiagnosed and underdiagnosed, and there is a lack of uniform efficacy assessment criteria for SCS, which causes great distress to patients and society. In this study, we will assesse the efficacy of cervical fixed-point rotational manipulation by combining HRV-related parameters and analyzing the correlation between the HRV and SCS. Methods/design: In this study, 90 participants will be randomly assigned at a 1:1:1 ratio into a test group (cervical fixed-point rotational manipulation manipulation group), a control group (sham manipulation group), or a Western medicine control group, with 30 participants in each group. All participants will be treated for a period of 4 weeks. The primary outcome indicators assessed is the HRV-related parameters, and the secondary outcome indicators are the NDI scale, NPQ scale, and HAMA scale. The assessment time points will be before and after treatment. The follow-up visits will be the first and sixth months after the end of treatment. Discussion: In this study, SCS are treated with cervical fixed-point rotational manipulation based on the biomechanical balance theory, and HRV-related parameters are used for assessment to analyze the effect of cervical fixed-point rotational manipulation on heart rate variability in patients with SCS. Clinical trial registration: http://itmctr.ccebtcm.org.cn/, identifier ITMCTR2025000569.

Indexed as

biomechanical equilibriumcervical fixed-point rotation manipulationheart rate variabilityrandomized controlled trialsympathetic cervical spondylosis

Identifiers

PMID41079364
PMCPMC12510945

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.