Evidence map›Paper›PMID 41079335›Full record

ArticleJournal of vascular surgery cases and innovative techniques2025

Large animal model validation of a fenestrated balloon-expandable stent for treatment of aortoiliac occlusive disease.

Sophia R Pyeatte, Maxwell C Braasch, John Cashin, Mohamed Zaghloul, Santiago Elizondo Benedetto, DeVaughn Rucker, Shahab Hafezi, Batool Arif, Guy M Genin, Mohamed A Zayed

Abstract read
In one paragraph

Article in Journal of vascular surgery cases and innovative techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sophia R PyeatteDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.
Maxwell C BraaschDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.
John CashinDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.
Mohamed ZaghloulDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.
Santiago Elizondo BenedettoDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.
DeVaughn RuckerDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.
Shahab HafeziDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.
Batool ArifDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.
Guy M GeninCenter of Cardiovascular Research Innovation in Surgery and Engineering, Washington University in St Louis, St Louis, MO.
Mohamed A ZayedDivision of Vascular Surgery, Department of Surgery, Section of Vascular Surgery, Washington University in St Louis, St Louis, MO.

Funding

Cardiovascular Innovation Program in Surgery & EngineeringT32HL170959 · NHLBI · WASHINGTON UNIVERSITY · PI Guy M Genin, Eric CLAUDE Leuthardt · 2024 to 2026
$1.6M
NHLBI NIH HHS T32 HL170959
6 · The paper itself

Abstract

The AortoIliac FENestrated (AIFEN) stent is a novel device that is designed for the endovascular management of aortoiliac occlusive disease while maintaining the natural aortoiliac anatomy and native bifurcation. Here, we report the first benchtop creation of this device through modification of a balloon-expandable covered stent and implanted in three large animal porcine aortoiliac segments. AIFEN stent placement was feasible and was maintained for 4 weeks in vivo. This first proof-of-concept AIFEN stent study demonstrates promising results and warrants further, rigorous evaluation to improve endovascular management of aortoiliac occlusive disease.

Indexed as

Aortic deviceAorto-iliac diseaseBench-top prototypeLarge animal testing

Identifiers

PMID41079335
PMCPMC12514496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.