ArticleFrontiers in surgery2025
Comparative analysis of hemostatic efficacy and safety: absorbable gelatin sponge with hemostatic fluid gelatin vs. tranexamic acid in posterior cervical expansive open-door laminoplasty.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Endoscopic posterior cervical canal decompression versus laminoplasty for two-level cervical spondylotic myelopathy: clinical outcomes and finite element analysis.Journal of orthopaedic surgery and research · 2026Article
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Authors and funding
7 authors.
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Abstract
Background: Posterior cervical expansive open-door laminoplasty carries significant intraoperative bleeding risks from Batson's plexus. While hemostatic agents such as absorbable gelatin sponge (GS), hemostatic fluid gelatin (HFG), and tranexamic acid (TXA) are widely used in spinal surgery, the efficacy and safety of combined strategies remain underexplored. This study aims to compare the hemostatic efficacy and safety of GS combined with HFG vs. GS combined with intravenous TXA in posterior cervical expansive open-door laminoplasty. Methods: A retrospective analysis was conducted on 75 patients undergoing posterior cervical expansive open-door laminoplasty at Ningxia Medical University General Hospital from January 2022 to January 2024, with stratification into two groups based on intraoperative hemostatic materials: the GS-HFG group (absorbable gelatin sponge combined with hemostatic fluid gelatin, Results: Operative duration demonstrated no statistically significant difference between the GS-HFG and GS-TXA groups (139.9 ± 21.7 min vs. 144.4 ± 30.7 min; Conclusion: Both the GS-HFG and GS-TXA protocols effectively reduce perioperative bleeding without increasing the risk of complications in posterior cervical expansive open-door laminoplasty.
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