ArticleOpen medicine (Warsaw, Poland)2025
Red cell distribution width predicts early kidney injury: A NHANES cross-sectional study.
Article in Open medicine (Warsaw, Poland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To investigate the association between red cell distribution width (RDW) and early kidney injury. Methods: Data were obtained from the 2003-2004 National Health and Nutrition Examination Survey, including 3,633 adult participants. Early kidney injury was defined according to the 2024 Kidney Disease: Improving Global Outcomes guidelines as eGFR ≥60 mL/min/1.73 m Results: After adjusting for confounders, there is a positive correlation between RDW and early kidney injury (OR = 1.26, 95% CI: 1.08-1.45, Conclusion: Elevated RDW is significantly associated with the risk of early kidney injury and is robust in the hypertensive population. RDW > 12.7% can serve as an economical and convenient screening threshold, especially suitable for early risk stratification of high-risk groups in resource-limited areas. Future prospective studies are needed to validate its causal mechanism and clinical utility.
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