ArticleFrontiers in endocrinology2025
Can the triglyceride-glucose index identify prediabetes in children and adolescents with obesity? a cross-sectional study.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Triglyceride-glucose index identifies early metabolic stress and β-cell vulnerability in pediatric obesity.World journal of pediatrics : WJP · 2026Article
- Screening for insulin resistance in children with abdominal obesity: sex-specific performance of TyG index, FGIR, and VAI.Physical activity and nutrition · 2026Article
- The Natural History of Prediabetes and Cardiovascular Disease in the Pediatric Population.Biomedicines · 2026Review
- Association between ZJU index and glycemic outcomes in individuals with impaired fasting glucose: a retrospective multicenter Chinese cohort study.Frontiers in endocrinology · 2026Article
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8 authors.
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Abstract
Purpose: This study aims to evaluate the triglyceride-glucose (TyG) index as a biomarker for identifying prediabetes mellitus (PDM) in children and adolescents with obesity and to compare its predictive ability with traditional indicators. Methods: A cross-sectional study was conducted with 213 children and adolescents with obesity, aged 8 to 18 years. Key inclusion criteria included obesity, defined as a BMI above the 95th percentile. Diagnostic criteria were based on fasting plasma glucose (FPG) and the oral glucose tolerance test (OGTT). Correlation analysis, least absolute shrinkage and selection operator (LASSO) logistic regression, logistic regression, and ROC curve analysis were performed to assess predictive performance. Results: The TyG index showed significant positive correlations with triglyceride (TG; Conclusion: The TyG index is a reliable and practical marker for identifying prediabetes in children and adolescents with obesity. Its predictive performance exceeds that of several conventional indicators, providing clinical value for early screening and intervention.
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