Evidence map›Paper›PMID 41079176›Full record

ArticleUrology case reports2025

Primary renal neuroendocrine tumor: A rare case and review of diagnostic and therapeutic challenges.

Kris Kokoneshi, Diego Gonzalez, Eileen Zhang, Fiona Wardrop, Ryan Antar, Sam Kwon, Sean Tafuri, Mohadese Behtaj, Andrew Hall, Michael Whalen

Abstract readCase Reports
In one paragraph

Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kris Kokoneshi
Diego Gonzalez
Eileen Zhang
Fiona Wardrop
Ryan Antar
Sam Kwon
Sean Tafuri
Mohadese Behtaj
Andrew Hall
Michael Whalen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary renal neuroendocrine tumors (NETs) are extremely rare and pose both diagnostic and therapeutic challenges due to their nonspecific presentation and overlap with more common renal masses. We report the case of a 49-year-old woman who presented with flank pain and was found to have a large well-differentiated Grade 2 renal NET. Histopathology revealed classic ribbon-like architecture with Ki-67 index of 3-7 %, and immunohistochemistry confirmed strong synaptophysin and CD56 positivity. Surgical resection via radical nephrectomy was curative. This case highlights the importance of histological evaluation and contributes to the limited literature review on renal NET diagnosis and management.

Identifiers

PMID41079176
PMCPMC12514538

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.