Evidence map›Paper›PMID 41079142›Full record

ArticleJAC-antimicrobial resistance2025

Association between daptomycin dosing and in-hospital mortality in patients with vancomycin-resistant

Kelly A Cairns, Iain J Abbott, Andrew A Udy, Trisha N Peel, Sue J Lee, Michael J Dooley, Anton Y Peleg

Abstract read
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In one paragraph

Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kelly A CairnsDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-9969-3972
Iain J AbbottDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0001-6590-6127
Andrew A UdyAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-6284-2022
Trisha N PeelDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0003-2370-2438
Sue J LeeDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-8409-4248
Michael J DooleyPharmacy Department, Alfred Health, Melbourne, Australia.
Anton Y PelegDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-2296-2126

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vancomycin-resistant Methods: A retrospective cohort study of adult patients receiving ≥3 days of definitive treatment for a first episode VRE Results: A total of 191 patients received definitive daptomycin ( Conclusions: In this contemporary study of predominantly high daptomycin doses, there was no association between daptomycin dose and 30-day in-hospital mortality but we did observe an association with microbiological failure.

Identifiers

PMID41079142
PMCPMC12509642

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.