Evidence map›Paper›PMID 41079014›Full record

ArticleAmerican journal of ophthalmology case reports2025

Salmonella-associated endophthalmitis in healthy infants: Two case reports and a review of the literature.

Asrar Alhejaili, Anas Alsaif, Firas Madani, Rawan N Althaqib, Valmore Semidey, Rafaa Babgi, Hamad M Alsulaiman

Abstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Asrar AlhejailiOculoplastic & Orbit Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Anas AlsaifOphthalmology Division, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Firas MadaniOphthalmology Department, King Abdulaziz University, Jeddah, Saudi Arabia.
Rawan N AlthaqibOculoplastic & Orbit Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Valmore SemideyVitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Rafaa BabgiPediatric Ophthalmology & Strabismus Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Hamad M AlsulaimanOculoplastic & Orbit Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report two cases of endophthalmitis caused by Salmonella species in healthy male infants. Background: Endogenous endophthalmitis is a rare but severe intraocular infection, often associated with systemic risk factors such as diabetes mellitus, malignancies, or immunosuppression. However, Observations: We present two cases of previously healthy male infants diagnosed with Salmonella-associated endogenous endophthalmitis (SAEE). The first patient, a 2-month-old male, presented with fever, left upper eyelid swelling, and decreased activity, and was found to have intraocular cultures that confirmed Salmonella species. Despite aggressive intravenous and intravitreal antibiotic therapy, the patient developed progressive intraocular inflammation, necessitating left eye evisceration.The second patient, a 5-month-old male, presented with fever and right eye inflammation. Examination revealed a hypopyon, hyphema, and dense vitritis in the right eye. Blood and vitreous cultures confirmed Salmonella infection, and magnetic resonance imaging (MRI) showed right peribulbar abscess formation. Due to poor response to medical therapy, right eye enucleation was performed. Conclusion and importance:

Indexed as

EnucleationEviscerationPediatric endophthalmitissalmonella

Identifiers

PMID41079014
PMCPMC12512158

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.