Evidence map›Paper›PMID 41079005›Full record

ArticleCase reports in medicine2025

Mixed-Type Carotid Sinus Syndrome in a Patient With Advanced Laryngeal Cancer: A Case Report.

Montaser Elkholy, Naisargee Solanki, Mohamed Abdelazeem, Zijin Lin, Yasemin Bahar, Zain U L Abideen Asad, M Chadi Alraies

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Montaser ElkholyDepartment of Medicine, Detroit Medical Center, Wayne State University, Detroit, Michigan, USA.
Naisargee SolankiDepartment of Medicine, Detroit Medical Center, Wayne State University, Detroit, Michigan, USA.
Mohamed AbdelazeemCardiovascular Department, UMass Chan-Baystate Medical Center, Springfield, Massachusetts, USA.
Zijin LinCollege of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, USA.
Yasemin BaharDepartment of Medicine, Detroit Medical Center, Wayne State University, Detroit, Michigan, USA.
Zain U L Abideen AsadDepartment of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
M Chadi AlraiesCardiovascular Institute, Detroit Medical Center, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0002-7874-4566

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck tumors can rarely cause carotid sinus syndrome (CSS), a condition characterized by bradycardia, hypotension, and syncope. A 68-year-old male with advanced laryngeal cancer presented with syncope. Examination revealed a fixed 5 cm submandibular mass. Computed tomography angiography (CTA) neck showed a large mass encasing the carotid arteries. During the hospital stay, the patient experienced recurrent bradycardia and hypotension, which were resolved when his neck was turned to the left. Diagnosis of mixed-subtype CSS secondary to tumor compression was assumed. Blood tests, EKG, and CT imaging ruled out other causes. The tumor's encasement of the carotid arteries likely triggered the carotid sinus reflex during head movement. Both cardioinhibitory and vasodepressor components were present, suggesting a mixed subtype of CSS. CSS should be considered in patients with head and neck cancer, presenting with unexplained bradycardia or hypotension. Multidisciplinary management is the key to accurate diagnosis and treatment.

Indexed as

bradycardiacancertreatment

Identifiers

PMID41079005
PMCPMC12513768

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