Evidence map›Paper›PMID 41078819›Full record

ArticleACS omega2025

Adsorption of Isoniazid on Aluminum Silicate Tubular Structures.

Ana Borrego-Sánchez, Carlos Gutiérrez-Ariza, C Ignacio Sainz-Díaz

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ana Borrego-SánchezDepartment of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Valencia 46100, Spain.
Carlos Gutiérrez-ArizaInstituto Andaluz de Ciencias de La Tierra, IACT-CSIC, Av. de Las Palmeras 4, Armilla 18100, Granada, Spain.
C Ignacio Sainz-DíazInstituto Andaluz de Ciencias de La Tierra, IACT-CSIC, Av. de Las Palmeras 4, Armilla 18100, Granada, Spain.ORCID https://orcid.org/0000-0001-8612-3826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tubular morphologies were formed using chemical gardens from aluminum salts, aluminum silicate, where the external surface is formed mainly by silicate and the inner surface is mainly aluminum oxide-hydroxide. Several stages are observed during the formation of tubular aluminosilicates using the Schlieren technique. In this work, the adsorption of a bioactive organic compound on the tubular structures formed from aluminum nitrate and sodium silicate was explored, obtaining surprising results. These tubular structures exhibit a notable adsorption capacity for organic compounds and can transport pharmaceutical drugs, such as isoniazid, yielding up to 10% of the solid weight. They could also be used as an excipient in medicines. Molecular modeling studies of this adsorption process corroborated that it is energetically favorable. This material appears to be a promising candidate for the development of novel drug delivery systems for the treatment of tuberculosis.

Identifiers

PMID41078819
PMCPMC12508985

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.