ArticleJournal of orthopaedic case reports2025
Association of Posterior Tibial Slope and Metaphysio-Diaphyseal Angle with Radiographic Severity of Knee Osteoarthritis in the Indian Population.
Article in Journal of orthopaedic case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Posterior tibial slope (PTS) and metaphysio-diaphyseal angle (MDA) are key anatomical angles influencing knee biomechanics. Their alterations may affect load distribution, contributing to osteoarthritis (OA) progression. Objective: To evaluate the association of PTS and MDA with Kellgren-Lawrence (KL) grades of knee OA and investigate their correlation. Materials and Methods: In this observational cross-sectional study, 92 patients with radiologically confirmed knee OA were recruited. Standard lateral and anteroposterior radiographs were used to measure PTS and MDA. OA severity was graded using the KL scale. Pearson's correlation and multiple regression analyses were performed using Statistical Package for the Social Sciences v24. Results: The mean PTS was 14.67° (standard deviation [SD] ± 3.03), and the mean MDA was 22.22° (SD ± 2.20). PTS and MDA showed a moderate positive correlation (r = 0.335, P < 0.01). MDA was significantly associated with KL grades (ρ = 0.3186, P = 0.0021), whereas PTS showed no statistically significant correlation (P = 0.157). Multiple regression confirmed MDA as a significant predictor of KL grade (P = 0.031). Conclusion: MDA demonstrates potential as a reliable radiographic marker for assessing OA severity. Although PTS shows biomechanical importance, it did not correlate significantly with radiographic severity in this study. These findings highlight the clinical utility of MDA in OA evaluation and surgical planning.
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