ArticlePreventive medicine reports2025
Burden of inflammatory enteritis caused by diarrheagenic
Article in Preventive medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Objective: Diarrheal diseases caused by diarrheagenic Methods: Using data from a national registry, we conducted a nationwide, retrospective analysis including hospitalized patients with DEC from 2016 to 2022. We used descriptive statistics and multivariable logistic regression to assess predictors of mortality. Results: We identified 265,754 hospitalizations related to DEC. Individuals aged ≥80 years exhibited the highest rates of hospitalization (516 per 100,000). Mortality rates increased with age. The elderly show the highest mortality rate (53.8 % of deaths). Women had higher mortality rates than men, especially in older age groups. Multivariable logistic regression identified age ≥ 80 years, comorbidities such as malignancy (odds ratio [OR] = 2.23, 95 % CI = 2.15, 2.3) and sepsis (OR = 3.6, 95 % CI = 3.47, 3.74), and coinfections with Conclusion: These findings underscore the growing burden of DEC-related diarrhea in Spain, particularly among aging populations, and highlight the need for targeted public health interventions, improved diagnostic protocols, and integrated care for patients with comorbidities.
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