Evidence map›Paper›PMID 41078460›Full record

ArticleMolecular therapy. Oncology2025

CXCL10-induced chemotaxis of

Shiori Eguchi, Wen Luo, Hongwen Zhu, Hai M Hoang, Changxin Xu, Gregory K Behbehani, Kazi L Tasneem, Janet Ayello, Mario Marcondes, Dean A Lee and 1 more

Abstract read
In one paragraph

Article in Molecular therapy. Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shiori EguchiDepartment of Pediatrics, New York Medical College, Valhalla, NY 10595, USA.
Wen LuoDepartment of Pediatrics, New York Medical College, Valhalla, NY 10595, USA.
Hongwen ZhuDepartment of Pediatrics, New York Medical College, Valhalla, NY 10595, USA.
Hai M HoangDepartment of Pediatrics, New York Medical College, Valhalla, NY 10595, USA.
Changxin XuJames J. Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA.
Gregory K BehbehaniDivision of Hematology, The Ohio State University, Columbus, OH 43210, USA.
Kazi L TasneemDepartment of Pediatrics, New York Medical College, Valhalla, NY 10595, USA.
Janet AyelloDepartment of Pediatrics, New York Medical College, Valhalla, NY 10595, USA.
Mario MarcondesNektar Therapeutics, San Francisco, CA 94158, USA.
Dean A LeeCenter for Childhood Cancer Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.
Mitchell S CairoDepartment of Pediatrics, New York Medical College, Valhalla, NY 10595, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OSA) has a dismal prognosis despite surgical resection and multiagent chemotherapy. While adoptive natural killer (NK) cell therapies have been successful in hematological malignancies, the application in solid tumors is challenging due to a tumor microenvironment (TME) that impairs NK cell tumor infiltration. Here, we found that

Indexed as

adoptive cell therapychemoattractionCXCL10CXCL11CXCL9CXCR3MT: Advancements in pediatric cancer therapynatural killer cellsNKTR-255osteosarcomatumor microenvironment

Identifiers

PMID41078460
PMCPMC12509742

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.