ArticleFood science & nutrition2025
Synergistic Effects of Dietary Protein and Vitamin E Intake on Reducing Metabolic-Associated Fatty Liver Disease Risk: Insights From NHANES [2017-2023] and Mendelian Randomization Study.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Nutritional intervention plays a pivotal role in managing metabolic-associated fatty liver disease (MAFLD), but the combined effect of protein and vitamin E on MAFLD remains indistinct. This study sought to evaluate the synergistic effects of these nutrients on MAFLD. This study enrolled 14,489 participants from the NHANES database. MAFLD was defined by liver fat accumulation and metabolic syndrome components. Multivariable logistic regression, restricted cubic spline modeling, and internal validation were applied to assess the dose-response and joint effects of protein and vitamin E, with gender stratification to explore effect heterogeneity. A Mendelian randomization (MR) approach was utilized to probe the causality between α-tocopherol and protein intake with MAFLD. Intake levels of protein and vitamin E were significantly reduced in individuals with MAFLD compared to the non-MAFLD group (All
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