Evidence map›Paper›PMID 41078394›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2025

Persistence Image from 3D Medical Image: Superpixel and Optimized Gaussian Coefficient.

Yanfan Zhu, Yash Singh, Khaled Younis, Shunxing Bao, Yuankai Huo

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanfan ZhuDepartment of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.
Yash SinghRadiology, Mayo Clinic, Rochester, MN, USA.
Khaled YounisMedAiConsult, Cleveland, OH, USA.
Shunxing BaoDepartment of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.
Yuankai HuoDepartment of Computer Science, Vanderbilt University, Nashville, TN, USA.

Funding

Controlling Quality and Capturing Uncertainty in Advanced Diffusion Weighted MRIR01EB017230 · NIBIB · VANDERBILT UNIVERSITY · PI LANDMAN, BENNETT A. · 2015 to 2024
$5.1M
RESOLUTION OF GLOMERULOSCLEROSISR01DK056942 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FOGO, AGNES B. · 2001 to 2021
$4.9M
Complementary ex vivo multimodal optical imaging and in vivo Raman spectroscopy to understand tissue dynamicsR01EB033385 · NIBIB · VANDERBILT UNIVERSITY · PI MAHADEVAN-JANSEN, ANITA, REESE, JOHN JEFFREY · 2022 to 2025
$2.6M
AI-empowered 3D Computer Vision and Image-Omics Integration for Digital Kidney HistopathologyR01DK135597 · NIDDK · VANDERBILT UNIVERSITY · PI Yuankai Huo · 2023 to 2026
$2.1M
Dual-wavelength endoscopic Raman probe for eosinophilic esophagitisR01DK132338 · NIDDK · VANDERBILT UNIVERSITY · PI MAHADEVAN-JANSEN, ANITA · 2022 to 2025
$1.7M
fMRI physiological signatures of aging and Alzheimer's DiseaseRF1MH125931 · NIMH · VANDERBILT UNIVERSITY · PI CHANG, CATHERINE ELIZABETH · 2021 to 2021
$1.1M
NIBIB NIH HHS R01 EB017230NIBIB NIH HHS R01 EB033385NIDDK NIH HHS R01 DK056942NIDDK NIH HHS R01 DK132338NIDDK NIH HHS R01 DK135597NIMH NIH HHS RF1 MH125931
6 · The paper itself

Abstract

Topological data analysis (TDA) uncovers crucial properties of objects in medical imaging. Methods based on persistent homology have demonstrated their advantages in capturing topological features that traditional deep learning methods cannot detect in both radiology and pathology. However, previous research primarily focused on 2D image analysis, neglecting the comprehensive 3D context. In this paper, we propose an innovative 3D TDA approach that incorporates the concept of superpixels to transform 3D medical image features into point cloud data. By Utilizing Optimized Gaussian Coefficient, the proposed 3D TDA method, for the first time, efficiently generate holistic Persistence Images for 3D volumetric data. Our 3D TDA method exhibits superior performance on the MedMNist3D dataset when compared to other traditional methods, showcasing its potential effectiveness in modeling 3D persistent homology-based topological analysis when it comes to classification tasks. The source code is publicly available at https://github.com/hrlblab/TopologicalDataAnalysis3D.

Indexed as

3D Medical ImagesPersistence ImagePersistent HomologyTopology Data Analysis

Identifiers

PMID41078394
PMCPMC12513536

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.