ArticleFrontiers in physiology2025
Analysis of the etiological characteristics of multidrug-resistant organisms and prognostic factors in ICU patients.
Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Real-World Effectiveness of Ceftazidime-Avibactam for Multidrug-Resistant Gram-Negative Pneumonia, Time-Stratified Risk Factors for Short- and Long-Term Mortality, and Inpatient Costs: A Multicenter Retrospective Cohort Study.Infectious diseases and therapy · 2026Article
- Article
- Clinical risk factors for multidrug-resistant organism infections in postoperative gastric cancer patients: an ICU-based retrospective analysis.BMC infectious diseases · 2026Article
- Pathogen characteristics and pre-index clinical factors associated with multidrug-resistant organism infections in intensive care unit patients.Frontiers in public health · 2026Observational
- Risk Factors and Medical Burden of Multidrug-Resistant Organism Infection in Hospitalized Patients with Pneumonia.Infection and drug resistance · 2026Article
- Analysis of the effectiveness of improving the testing rate of pathogenicity specimens prior to the use of antibiotics in Shandong Province, 2014-2023.Frontiers in public health · 2025Article
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Authors and funding
5 authors.
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Abstract
Background: Multidrug-resistant organism (MDRO) infections contribute to high mortality in intensive care unit (ICU) patients, yet their specific pathogen profile and mortality risk factors are inadequately characterized. Objective: In this study, we aim to investigate MDRO infections in ICU patients, identify prevalent pathogens, and evaluate risk factors associated with 28-day mortality. Methods: A retrospective study of 260 ICU patients with MDRO infections (resistant to ≥3 antimicrobial classes) analyzed the specimen types, infection sites, and pathogens. Patients were grouped (survival group and non-survival group) based on 28-day survival outcomes. Multivariate logistic regression identified prognostic factors, and the model's validity, fit, and discriminatory power were assessed. Results: In ICU patients with MDRO infections, sputum was the most common test specimen, with the respiratory system as the main infection site. Pathogenic bacteria primarily included Conclusion: ICU patients with MDRO infections exhibit diverse pathogens. Prompt preventive and control measures should be implemented based on the characteristics of MDRO infections and high-risk factors associated with prognosis to reduce the risk of death following MDRO infections.
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