ReviewInflammatory bowel diseases2025
Towards IBD Prediction and Prevention: The Contribution of Genetics and Genomics.
Review in Inflammatory bowel diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
This review appraises the current genetic and genomic knowledge in inflammatory bowel disease (IBD) with regard to diagnosis, therapy, and medicine for ulcerative colitis and Crohn's disease. The results of numerous genetic and genome-wide association studies leave no doubts that IBD has an undeniable and biologically relevant genetic component, deeply rooted in the patient individual genetic makeup. Decades of research have firmly established that numerous genetic loci are linked to IBD, making the individuals who inherit them significantly more susceptible to developing ulcerative colitis or Crohn's disease. IBD genetics are very heterogeneous and variable when considering natural history, clinical features, age of onset, and the discrete subgroups that are affected. The review interrogates the risk for IBD and highlights some opportunities that may lead to the future possibility of preventing IBD. If strategies for prevention, early detection, early intervention, or even avoidance are to be developed, the obvious genetic underpinnings of IBD cannot be ignored.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.