ArticleMagnetic resonance in medicine2026
High-resolution deuterium metabolic imaging of the human brain at 9.4 T using phase-cycled balanced SSFP spectral-spatial acquisitions.
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Atlas of Brain Glucose Metabolism Using Deuterium Metabolic Imaging at 3 T.Magnetic resonance in medicine · 2026Article
- Advanced methods in deuterium metabolic imaging.Magma (New York, N.Y.) · 2026Review
- High-resolution deuterium metabolic imaging of the human brain at 9.4 T using phase-cycled balanced SSFP spectral-spatial acquisitions.Magnetic resonance in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeThe aim was to improve the sensitivity and robustness against B
methodsWe investigated two variants of phase-cycled bSSFP acquisitions, namely uniformly weighted multi-echo and acquisition-weighted chemical shift imaging (CSI) to improve the SNR of DMI in the brain after oral [6,6'-
resultsHigh-resolution whole-brain dynamic DMI maps were obtained for all acquisitions. The CSI variant of phase-cycled bSSFP achieved an average SNR increase of 16% and 25% for glucose and glutamate + glutamine (Glx), respectively, compared to the SNR-optimized vendor's standard CSI. Phase-cycling improved the bSSFP metabolite estimation and provided additional spectral encoding at the cost of a 10% to 20% SNR loss. Compared to the CSI variant of bSSFP acquisition, the multi-echo variant exhibited up to 35% lower SNR performance because of uniform k-space weighting and less efficient readout. However, it achieved higher resolutions than acquisition-weighted CSI protocols and showed several qualitative improvements.
conclusionWe demonstrated the feasibility of using two phase-cycled bSSFP acquisitions for off-resonance insensitive high-resolution [6,6'-
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.