Evidence map›Paper›PMID 41078117›Full record

ArticleJournal of cachexia, sarcopenia and muscle2025

Subcutaneous Adipose Tissue Radiation Attenuation Is Associated With Increased 1-Year Mortality in Polytrauma Patients.

Leanne L G C Ackermans, Jasper C Stokroos, David P J Van Dijk, Bjorn Winkens, Martijn Poeze, Leonard Wee, Ralph Brecheisen, Steven M W Olde Damink, Jan A Ten Bosch, Taco J Blokhuis

Abstract read
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leanne L G C AckermansDepartment of Traumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.ORCID 0000-0003-1583-7383
Jasper C StokroosDepartment of Traumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
David P J Van DijkDepartment of Surgery, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Bjorn WinkensDepartment of Methodology and Statistics, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht.
Martijn PoezeDepartment of Traumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Leonard WeeDepartment of Radiation Oncology (MAASTRO), GROW School for Oncology and Development Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Ralph BrecheisenDepartment of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Steven M W Olde DaminkDepartment of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Jan A Ten BoschDepartment of Traumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Taco J BlokhuisDepartment of Traumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.

Funding

EIT Food for EIT Health and Eurostars MAS E! 114232
6 · The paper itself

Abstract

backgroundPolytrauma patients with an Injury Severity Score (ISS) ≥ 16 have a high mortality rate. Early identification of patients at risk of mortality is key. Different risk stratification models are available; however, body composition on third lumbar computed tomography (L3 CT) is not routinely used. The aim of this study is to determine the effect of CT body composition on 1-year mortality in adult polytrauma patients.

methodsBody composition analysis (L3 CT) was performed on 593 adult polytrauma patients. The associations with 1-year mortality were assessed using uni- and multivariable logistic regression analysis. As a sensitivity analysis, 1-year mortality was analysed using Kaplan-Meier survival curves, log-rank tests and Cox regression.

resultsThe study population was predominantly male (69.5%), with a mean age of 55 (±20) years and an average BMI of 25.34 kg/m

conclusionsThis study demonstrated that subcutaneous adipose tissue radiation attenuation on emergency trauma CT scans is significantly associated with 1-year mortality in adult polytrauma patients. Additionally, we found a significant effect of age and ISS on 1-year mortality. Incorporating body composition analysis could lead to a better selection of patients at risk for 1-year mortality and aid in treatment decision-making.

Indexed as

Multiple TraumaSubcutaneous FatAdultAgedBody CompositionFemaleHumansInjury Severity ScoreMaleMiddle AgedTomography, X-Ray Computedadipose tissuebody compositioncomputed tomographymortalitypolytrauma

Identifiers

PMID41078117
PMCPMC12516153

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.