Evidence map›Paper›PMID 41078100›Full record

ReviewJournal of cellular and molecular medicine2025

Research Trends of Hepatic Stellate Cells in Hepatoma: A Bibliometric Analysis.

Qingbin Wu, Xiuju Ye, Yuhang Wang, Bingwei Li, Qin Wang, Xiaochen Yuan, Jianqun Han, Ailling Li, Hongwei Li, Ruijuan Xiu

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qingbin WuInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0002-7522-3562
Xiuju YeHealth Management Center, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yuhang WangSchool of Basic Medicine, Capital Medical University, Beijing, China.
Bingwei LiInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Qin WangInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Xiaochen YuanInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Jianqun HanInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Ailling LiInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Hongwei LiInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Ruijuan XiuInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Funding

the CAMS Innovation Fund for Medical Sciences (CIFMS) 2022-I2M-1-026
6 · The paper itself

Abstract

This study aims to delineate the global landscape, knowledge structure, and emerging trends of research on hepatic stellate cells (HSCs) in hepatoma from 2009 to 2023 using bibliometric methods. We retrieved 510 relevant publications from the Web of Science Core Collection to analyse annual growth, country/region distribution, key contributors, and collaboration networks. The results show a significant increase in annual publications since 2018, with China, the United States, and Japan emerging as the primary research forces, and China leading in publication volume. Citation analysis indicates that the United States has the greatest research impact. Keyword co-occurrence and cluster analysis revealed core research themes, such as liver fibrosis, tumour microenvironment, and apoptosis, while identifying emerging hotspots like gene therapy and nanotechnology. The collaboration network exhibits close-knit cooperation within existing teams but a need for strengthening new international and interdisciplinary partnerships. This study systematically maps the knowledge domain of HSC research in hepatoma, offering data-driven insights for future research directions and international collaboration.

Indexed as

BibliometricsBiomedical ResearchCarcinoma, HepatocellularHepatic Stellate CellsLiver NeoplasmsHumansTumor Microenvironmentbibliometric analysishepatic stellate cellshepatomainterdisciplinary

Identifiers

PMID41078100
PMCPMC12516157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.