Evidence map›Paper›PMID 41078008›Full record

ArticleClinical and translational medicine2025

Soluble IL-2R: A potential therapeutic target for mitochondrial dysfunction in post-COVID fatigue syndrome.

Laura P Brown, Jai Joshi, Kate Kosmac, Douglas E Long, Logan Scott, Salim El-Amouri, Ashley A Montgomery-Yates, Anna G Kalema, Jamie L Sturgill, Hemendra Vekaria and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Laura P BrownDepartment of Physiology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0001-5683-2074
Jai JoshiDepartment of Physiology, University of Kentucky, Lexington, Kentucky, USA.
Kate KosmacDepartment of Physical Therapy, Augusta University, Augusta, Georgia, USA.ORCID https://orcid.org/0000-0002-5247-4684
Douglas E LongCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-6770-5764
Logan ScottDepartment of Physiology, University of Kentucky, Lexington, Kentucky, USA.
Salim El-AmouriDepartment of Physiology, University of Kentucky, Lexington, Kentucky, USA.
Ashley A Montgomery-YatesDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-2899-7469
Anna G KalemaDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Kentucky, Lexington, Kentucky, USA.
Jamie L SturgillDepartment of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0001-8856-3227
Hemendra VekariaSpinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0001-5945-5235
Patrick G SullivanSpinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0001-7418-4760
Dylan WilburnDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID https://orcid.org/0000-0001-7043-2341
Panagiotis KoutakisDepartment of Biology, Baylor University, Waco, Texas, USA.ORCID https://orcid.org/0000-0002-8352-5667
Christine M LathamCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-0956-9688
Christopher S FryCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-4207-6594
Philip A KernCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-4761-7417
Benjamin F MillerAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.ORCID https://orcid.org/0000-0003-3283-0685
Esther E Dupont-VersteegdenCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0001-5576-9659
Ahmed IsmaeelDepartment of Physiology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0003-4025-3945
Kirby P MayerCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0003-3844-3846
Yuan WenDepartment of Physiology, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-3210-1629

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
UK ASCEND (Achieving Success in Community-Engaged research to elimiNate Disparities)P50MD019476 · NIMHD · UNIVERSITY OF KENTUCKY · PI Lovoria B Williams · 2024 to 2026
$2.4M
Muscle and physical function recovery after acute critical illnessR01AR081002 · NIAMS · UNIVERSITY OF KENTUCKY · PI Esther E Dupont-Versteegden · 2023 to 2026
$1.7M
Cellular and Physical Function Outcomes Leading to Failed Muscle Recovery After Critical IllnessK23AR079583 · NIAMS · UNIVERSITY OF KENTUCKY · PI Kirby P Mayer · 2022 to 2026
$744k
Contribution of ribosome specialization to the pathophysiology of muscular dystrophyR00AR081367 · NIAMS · UNIVERSITY OF KENTUCKY · PI YUAN WEN · 2024 to 2026
$719k
NIAMS NIH HHS K23 AR079583NIAMS NIH HHS R00 AR081367NIAMS NIH HHS R01 AR081002NIH HHS K23-AR079583NIH HHS P50MD019476NIH HHS R00-AR081367NIH HHS R01-AR081002NIH HHS UL1TR001998University of Kentucky College of Health Sciences Pilot Grant Program
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41078008
PMCPMC12516084

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.