Evidence map›Paper›PMID 41077860›Full record

ArticleACR open rheumatology2025

IL-17

Rui Imai, Yi Li, Hao Li, Anwesha Kar, Rong Fu, Wei Li, Vasileios C Kyttaris, George C Tsokos

Abstract read
In one paragraph

Article in ACR open rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rui ImaiBeth Israel Deaconess Medical Center, Boston, Massachusetts.
Yi LiBeth Israel Deaconess Medical Center, Boston, Massachusetts.
Hao LiBeth Israel Deaconess Medical Center, Boston, Massachusetts.
Anwesha KarBeth Israel Deaconess Medical Center, Boston, Massachusetts.
Rong FuBeth Israel Deaconess Medical Center, Boston, Massachusetts.
Wei LiBeth Israel Deaconess Medical Center, Boston, Massachusetts.
Vasileios C KyttarisBeth Israel Deaconess Medical Center, Boston, Massachusetts.ORCID https://orcid.org/0000-0001-7652-3826
George C TsokosBeth Israel Deaconess Medical Center, Boston, Massachusetts.ORCID https://orcid.org/0000-0001-9589-2360

Funding

Expanded Double Negative T cells in SLE.R01AI085567 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TSOKOS, GEORGE C · 2010 to 2025
$6.8M
NIH HHS R01AI085567
6 · The paper itself

Abstract

objectiveT cell receptor αβ

methodsFlow cytometry was used to analyze DN T cells in lupus-prone MRL/lpr mice and patients with SLE. IL-17

resultsIL-17

conclusionThe observation of nonoverlapping IL-10

Identifiers

PMID41077860
PMCPMC12516011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.