Evidence map›Paper›PMID 41077846›Full record

ReviewRegenerative medicine2025

The feasibility of 3D bioprinting for bone regeneration: key challenges and future directions.

Thiago Domingues Stocco, Rafael Prado de Carvalho, Hugo Cesar Oliveira Silva, Taynara Soares de Melo Sousa

Abstract readReview
In one paragraph

Review in Regenerative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thiago Domingues StoccoBioRegenera.Lab, Bioengineering Program, Scientific and Technological Institute, Brasil University, São Paulo, Brazil.ORCID 0000-0003-3235-0251
Rafael Prado de CarvalhoBioRegenera.Lab, Bioengineering Program, Scientific and Technological Institute, Brasil University, São Paulo, Brazil.
Hugo Cesar Oliveira SilvaFaculty of Medical Sciences, State University of Campinas, Campinas, Brazil.
Taynara Soares de Melo SousaSanto Amaro University, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) bioprinting has emerged as a promising biofabrication strategy for bone regeneration, offering unprecedented control over the spatial distribution of cells, biomaterials, and bioactive cues. By enabling the production of anatomically customized grafts with microarchitectural complexity and biological functionality, bioprinting holds potential to overcome limitations associated with autografts, allografts, and synthetic bone substitutes. This review provides a comprehensive synthesis of recent advances in bioprinting technologies, bioink design, and recent

Indexed as

BioprintingBone RegenerationPrinting, Three-DimensionalTissue EngineeringAnimalsHumansTissue Scaffoldsbioprintingbone fracturesBone regenerationtissue engineering

Identifiers

PMID41077846
PMCPMC12607285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.