Evidence map›Paper›PMID 41077759›Full record

ArticleActa obstetricia et gynecologica Scandinavica2026

Gestational diabetes mellitus and offspring health: A 12-year register-based analysis of specialized health care utilization in Finland.

Jenni Kinnunen, Hilkka Nikkinen, Elina Keikkala, Sanna Mustaniemi, Mika Gissler, Hannele Laivuori, Johan G Eriksson, Eero Kajantie, Marja Vääräsmäki

Abstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jenni KinnunenResearch Unit of Clinical Medicine, Medical Research Center, University of Oulu, Oulu, Finland.ORCID 0000-0001-5287-7582
Hilkka NikkinenResearch Unit of Clinical Medicine, Medical Research Center, University of Oulu, Oulu, Finland.
Elina KeikkalaResearch Unit of Clinical Medicine, Medical Research Center, University of Oulu, Oulu, Finland.
Sanna MustaniemiResearch Unit of Clinical Medicine, Medical Research Center, University of Oulu, Oulu, Finland.ORCID 0000-0003-4483-830X
Mika GisslerDepartment of Data and Analytics, Finnish Institute for Health and Welfare, Helsinki, Finland.ORCID 0000-0001-8254-7525
Hannele LaivuoriMedical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0003-3212-7826
Johan G ErikssonDepartment of Obstetrics and Gynecology and Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Eero KajantieResearch Unit of Clinical Medicine, Medical Research Center, University of Oulu, Oulu, Finland.
Marja VääräsmäkiResearch Unit of Clinical Medicine, Medical Research Center, University of Oulu, Oulu, Finland.

Funding

Academy of FinlandDiabetes Research FoundationJuho Vainion SäätiöLastentautien TutkimussäätiöMedical Research Center OuluNational Institute for Health and Welfare FinlandNovo Nordisk FondenPäivikki ja Sakari Sohlbergin SäätiöResearch Funds of Helsinki University HospitalResearch Funds of Oulu University HospitalSigne ja Ane Gyllenbergin SäätiöSigrid Juséliuksen SäätiöSuomen Lääketieteen SäätiöYrjö Jahnssonin Säätiö
6 · The paper itself

Abstract

introductionGestational diabetes mellitus (GDM) is associated with various health risks in offspring. We investigated the effect of GDM exposure on offspring morbidity in a population-based cohort, assessed by the utilization of specialized health care services up to 12 years of age. MATERIAL AND

methodsThis register-based study, part of the Finnish Gestational Diabetes (FinnGeDi) study, included all singleton children born in Finland in 2009, captured from the Medical Birth Registry. Mothers of children in the study cohort underwent comprehensive screening for GDM. The study cohort included 6235 (11.1%) GDM-exposed children and 49 484 unexposed children. Utilization of specialized health care services was measured as the number of outpatient visits and inpatient treatment episodes (including duration in days). Data were obtained from the Finnish Care Register for Health Care up to 12 years of age and were analyzed separately for early childhood (0-2 years), preschool age (3-6 years), and school age (7-12 years) also. Maternal, birth, and child-related factors were considered, including maternal age, pre-pregnancy body mass index (BMI), parity, maternal hypertensive disorders, socioeconomic status (SES), smoking status, mode of delivery, preterm birth, small for gestational age, and child sex in the adjustment model.

resultsChildren exposed to maternal GDM had a higher incidence of outpatient visits than unexposed children (adjusted incidence rate ratio [IRR] 1.10, 95% confidence interval [CI] 1.07-1.13). Among children with multiple outpatient care visits (the highest quartile), GDM-exposed children were overrepresented in early childhood (adjusted odds ratio [aOR] 1.08, 95% CI: 1.00-1.15), preschool age (aOR 1.12, 95% CI: 1.05-1.19), and school age (aOR 1.11, 95% CI: 1.04-1.19). Children exposed to GDM were also more likely to require inpatient treatment than unexposed children (adjusted IRR 1.14, 95% CI: 1.10-1.19). The difference was not explained by shorter episodes (adjusted IRR 1.20, 95% CI: 1.16-1.24 for inpatient treatment days).

conclusionsChildren exposed to maternal GDM required more specialized health care services than unexposed children, with increased utilization of specialized health care observed across all age categories up to 12 years of age.

Indexed as

Child HealthDiabetes, GestationalPatient Acceptance of Health CarePrenatal Exposure Delayed EffectsAdultChildChild, PreschoolFemaleFinlandHumansInfantInfant, NewbornMalePregnancyRegistriesgestational diabeteshealth care utilizationhospitalizationmaternal exposuremorbidityoffspring

Identifiers

PMID41077759
PMCPMC12746197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.