Evidence map›Paper›PMID 41077707›Full record

ArticleThe journal of obstetrics and gynaecology research2025

Construction and evaluation of a risk prediction model for postoperative deep vein thrombosis in gynecological patients.

Jing Lu, Huihui Zhu, Xilian Guo, Yan Jia, Jian Liu, Can Cui, Yang Deng

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Article in The journal of obstetrics and gynaecology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 citing papers in PubMed.

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5 · Who and what money

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7 authors.

Jing LuDepartment of Gynecology, Taiyuan Maternal and Child Health Care Hospital, Taiyuan City, China.
Huihui ZhuDepartment of Gynecology, Taiyuan Maternal and Child Health Care Hospital, Taiyuan City, China.
Xilian GuoDepartment of Gynecology, Taiyuan Maternal and Child Health Care Hospital, Taiyuan City, China.
Yan JiaDepartment of Gynecology, Taiyuan Maternal and Child Health Care Hospital, Taiyuan City, China.
Jian LiuDepartment of Gynecology, Taiyuan Maternal and Child Health Care Hospital, Taiyuan City, China.
Can CuiDepartment of Gynecology, Taiyuan Maternal and Child Health Care Hospital, Taiyuan City, China.
Yang DengDepartment of Gynecology, Taiyuan Maternal and Child Health Care Hospital, Taiyuan City, China.ORCID https://orcid.org/0009-0001-7324-065X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the predictive role of a risk assessment model constructed using Caprini score combined with D-dimer in gynecological postoperative patients for the occurrence of deep vein thrombosis.

methodsPatients scheduled for gynecological surgery at our hospital between January 2018 and April 2024 were included. This study included 136 patients, with 35 cases in the DVT group and 101 cases in the non-DVT group. General information, intraoperative parameters, D-dimer levels, Caprini Score, lower extremity Doppler ultrasonography, and intervention methods were collected. Logistic regression analysis and a combined model were employed to analyze the factors influencing the occurrence of DVT.

resultsCompared to non-DVT patients, the DVT group had a significantly older age (p = 0.035), higher hypertension prevalence (p = 0.025), and more complex surgeries (p = 0.004). Pre-discharge D-dimer levels and pre-/postoperative Caprini scores were markedly elevated in DVT patients (p < 0.05). Critically, logistic regression identified pre-discharge D-dimer levels (p < 0.001), preoperative Caprini score (p = 0.003), and postoperative Caprini score (p < 0.001) as independent risk factors for DVT. The combined prediction model integrating these factors achieved an AUC of 0.812, demonstrating high discriminative power for postoperative DVT occurrence.

conclusionThe predictive value of the DVT prediction model constructed using the Caprini score in combination with D-dimer for the occurrence of DVT is high. The combined predictive model can be further promoted in clinical practice to take appropriate preventive measures to reduce the likelihood of DVT occurrence and to intervene promptly in existing risk factors.

Indexed as

Gynecologic Surgical ProceduresPostoperative ComplicationsVenous ThrombosisAdultAgedFemaleFibrin Fibrinogen Degradation ProductsHumansMiddle AgedRisk AssessmentRisk FactorsFibrin Fibrinogen Degradation Productsfibrin fragment DCaprini scoreD‐dimerdeep vein thrombosisgynecologicalrisk prediction model

Identifiers

PMID41077707
PMCPMC12516021

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.