Evidence map›Paper›PMID 41077623›Full record

ArticleCell proliferation2026

Luteolin Inhibits NLRP3 Inflammasome Activation to Ameliorate DSS-Induced Colitis by Regulating AMPK Signalling.

Lianxiang Luo, Fangfang Huang, Guixuan Fang, Yiming Sun, Liyan Deng, Yinglin Liao, Xinming Chen, Zhuosi Chen, Xinxun Lin

Abstract readLetter
In one paragraph

Article in Cell proliferation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Natural Molecules for Brain Health and Resilience.International journal of molecular sciences · 2026
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lianxiang LuoSchool of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang, Guangdong, China.ORCID https://orcid.org/0000-0002-3391-9713
Fangfang HuangGraduate School, Guangdong Medical University, Zhanjiang, Guangdong, China.
Guixuan FangGraduate School, Guangdong Medical University, Zhanjiang, Guangdong, China.
Yiming SunThe First Clinical College, Guangdong Medical University, Zhanjiang, Guangdong, China.
Liyan DengThe First Clinical College, Guangdong Medical University, Zhanjiang, Guangdong, China.
Yinglin LiaoThe First Clinical College, Guangdong Medical University, Zhanjiang, Guangdong, China.
Xinming ChenThe First Clinical College, Guangdong Medical University, Zhanjiang, Guangdong, China.
Zhuosi ChenThe First Clinical College, Guangdong Medical University, Zhanjiang, Guangdong, China.
Xinxun LinThe First Clinical College, Guangdong Medical University, Zhanjiang, Guangdong, China.

Funding

National Natural Science Foundation of China 82370564
6 · The paper itself

Abstract

Luteolin alleviates DSS-induced ulcerative colitis in mice by targeting the NLRP3 inflammasome, as it shows no effect in NLRP3

Indexed as

AMP-Activated Protein KinasesColitisInflammasomesLuteolinNLR Family, Pyrin Domain-Containing 3 ProteinAnimalsCalciumInterleukin-1betaLipid MetabolismMacrophagesMetabolomeMiceMice, Inbred C57BLMice, KnockoutReactive Oxygen SpeciesSignal TransductionAMP-Activated Protein KinasesCalciumInflammasomesInterleukin-1betaLuteolinNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseReactive Oxygen Species

Identifiers

PMID41077623
PMCPMC12877959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.