Evidence map›Paper›PMID 41077435›Full record

ReviewThe Surgical clinics of North America2025

Microbiome of Young and Later-Onset Colorectal Cancer.

Norman J Galbraith, Michael G White

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Surgical clinics of North America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Norman J GalbraithDivision of Surgery, Department of Colon and Rectal Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Michael G WhiteDivision of Surgery, Department of Colon and Rectal Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: mgwhite@mdanderson.org.

Funding

CTSA K12 Program at The University of Texas Health Science Center at HoustonK12TR004908 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Charles C Miller, JON E. TYSON · 2024 to 2026
$2.9M
NCATS NIH HHS K12 TR004908
6 · The paper itself

Abstract

Young-onset colorectal cancer (YOCRC) is increasingly common in the Western world. This has been attributed to changes in diet, lifestyle, and other environmental factors which all influence the gut microbiome. This review summarizes a small number of studies that have demonstrated differences in the microbiome of YOCRC, assessed in the stool and tumoral compartment. These populations are distinct from LOCRC and are prognostically important. Further research may reveal their role in the pathogenesis of this epidemic, and microbiological interventions can alter or augment existing treatment responses.

Indexed as

Colorectal NeoplasmsGastrointestinal MicrobiomeAge of OnsetHumansColorectal cancerEarly-onsetMicrobiomeYoung-onset

Identifiers

PMID41077435
PMCPMC13080724

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.