Evidence map›Paper›PMID 41077307›Full record

ReviewAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2026

Best practices in mouse models of skin transplantation.

Thiago J Borges, Scott M Krummey, Mandy L Ford

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thiago J BorgesCenter for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Scott M KrummeyDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Mandy L FordDepartment of Surgery and Emory Transplant Center, Emory University, Atlanta, Georgia, USA. Electronic address: mandy.ford@emory.edu.

Funding

CD11b: A Novel Alternate Receptor for CD154 during AlloimmunityR01AI152516 · NIAID · EMORY UNIVERSITY · PI FORD, MANDY L · 2020 to 2025
$4.6M
Determinants of T Cell Fate in Transplantation ToleranceR01AI164716 · NIAID · EMORY UNIVERSITY · PI Mandy L Ford · 2022 to 2026
$3.6M
NIAID NIH HHS R01 AI152516NIAID NIH HHS R01 AI164716
6 · The paper itself

Abstract

The murine skin transplant model has been used for decades as a sensitive in vivo model in which to dissect mechanistic aspects of alloreactivity. Indeed, seminal work defining the nature of alloreactivity was accomplished in the murine skin graft model. In the modern era, the incorporation of genetically altered animals, pharmacologic manipulation, and multiomics approaches in the murine skin graft model has significantly increased the mechanistic insight that can be gleaned from these studies. Because skin grafts are not primarily vascularized, the immune response against them is dominated by a CD8

Indexed as

Disease Models, AnimalGraft RejectionSkin TransplantationAnimalsGraft SurvivalHumansMiceModels, AnimalCD4(+) T lymphocyteCD8(+) T lymphocytemouse modelskin transplantationT cell-mediated rejection

Identifiers

PMID41077307
PMCPMC12697377

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.