Evidence map›Paper›PMID 41077131›Full record

ArticleJournal of thrombosis and haemostasis : JTH2026

Macrophage Plg-R

Lindsey A Miles, Hongdong Bai, Sagarika Chakrabarty, Nagyung Baik, Yuqing Zhang, Robert J Parmer, Fahumiya Samad

Abstract read
In one paragraph

Article in Journal of thrombosis and haemostasis : JTH, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lindsey A MilesDepartment of Cell and Molecular Biology, Scripps Research, La Jolla, California, USA.
Hongdong BaiDepartment of Medicine, Veterans Administration San Diego Healthcare System, San Diego, California, USA.
Sagarika ChakrabartySan Diego Biomedical Research Institute, San Diego, California, USA.
Nagyung BaikDepartment of Cell and Molecular Biology, Scripps Research, La Jolla, California, USA.
Yuqing ZhangDepartment of Cell and Molecular Biology, Scripps Research, La Jolla, California, USA.
Robert J ParmerDepartment of Medicine, Veterans Administration San Diego Healthcare System, San Diego, California, USA; Department of Medicine, University of California San Diego, La Jolla, California, USA.
Fahumiya SamadSan Diego Biomedical Research Institute, San Diego, California, USA. Electronic address: fsamad@sdbri.org.

Funding

Regulation of plasminogen-dependent cell functions by the novel receptor, Plg-RKTR01HL081046 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A · 2007 to 2024
$8.7M
A Novel Plasminogen Receptor Promotes Adipose Function and Metabolic HomeostasisR01HL149511 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A, PARMER, ROBERT J · 2019 to 2022
$3.0M
Therapeutic Opportunities of Targeting Tissue Factor Signaling in ObesityR01HL104232 · NHLBI · TORREY PINES INST FOR MOLECULAR STUDIES · PI SAMAD, FAHUMIYA · 2011 to 2014
$2.4M
BLRD VA I01 BX003933NHLBI NIH HHS R01 HL081046NHLBI NIH HHS R01 HL104232NHLBI NIH HHS R01 HL149511
6 · The paper itself

Abstract

backgroundPlg-R

objectivesWe investigated the role of Plg-R

methodsMice deficient in Plg-R

resultsPlg-R

conclusionThese findings underscore the critical role of macrophage Plg-R

Indexed as

Diet, High-FatEnergy MetabolismFatty LiverLiverMacrophagesNon-alcoholic Fatty Liver DiseaseObesityAnimalsDisease Models, AnimalHepatocytesLipogenesisMaleMiceMice, Inbred C57BLMice, KnockoutPhenotypeadipose inflammationmacrophagesMASLDobesityplasminogen receptor

Identifiers

PMID41077131
PMCPMC12671604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.