Evidence map›Paper›PMID 41076870›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

An unusual association between HIV and Creutzfeldt-Jakob disease in a patient from northeastern Brazil.

José Wagner Leonel Tavares-Júnior, Francisco José Basílio, Francisco Edson Buhamra Abreu, Lucas Rodrigues Tomaz Dos Santos, Pablo Picasso de Araújo Coimbra, Érico Antonio Gomes de Arruda

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In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

José Wagner Leonel Tavares-JúniorUniversidade Federal do Ceará, Departamento de Medicina Clínica, Fortaleza, CE, Brazil. Electronic address: wagnerleoneljr@gmail.com.
Francisco José BasílioHospital São José de Doenças Infecciosas, Fortaleza, CE, Brazil.
Francisco Edson Buhamra AbreuHospital São José de Doenças Infecciosas, Fortaleza, CE, Brazil.
Lucas Rodrigues Tomaz Dos SantosUniversidade Estadual do Ceará, Fortaleza, CE, Brazil.
Pablo Picasso de Araújo CoimbraCentro Universitário Christus (Unichristus), Fortaleza, CE, Brazil.
Érico Antonio Gomes de ArrudaHospital São José de Doenças Infecciosas, Fortaleza, CE, Brazil; Universidade Estadual do Ceará, Fortaleza, CE, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prion diseases are significant contributors to rapidly progressive dementia. Among these conditions, sporadic Creutzfeldt-Jakob Disease (CJD) is the most prevalent, characterized by its rarity, lack of treatment options, and rapid progression to fatality. Diagnosis relies on a combination of clinical symptoms and specific alterations detected in brain MRI, EEG, and CSF analysis. The present study details the case of a 53-year-old individual from Fortaleza, Brazil, diagnosed with sporadic CJD, confirmed through clinical presentation and a series of diagnostic evaluations, including 14-3-3 protein detection and RT-QuIC analysis. Differential diagnoses were considered to rule out other rapidly progressing conditions, such as infectious and immune-related diseases, ultimately leading to a likely diagnosis of sporadic CJD.

Indexed as

Creutzfeldt-Jakob SyndromeHIV Infections14-3-3 ProteinsBrazilDiagnosis, DifferentialHumansMagnetic Resonance ImagingMiddle Aged14-3-3 ProteinsCreutzfeldt-Jakob diseaseHIV infectionPrion diseasesRapidly progressive dementia

Identifiers

PMID41076870
PMCPMC12547893

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