Evidence map›Paper›PMID 41076517›Full record

ArticleJournal of nanobiotechnology2025

Tungsten disulfide atomic crystals with RONS scavenging and liver targeting capabilities for acetaminophen-induced acute liver injury therapy.

Ziwen Xiao, Yu Liu, Zhenchao Tao, Yu Zhang, Qian Chen, Zhaohua Miao, Zhengbao Zha, Yan Ma, Hua Wang, Deyan Gong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ziwen Xiao *School of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.
Yu Liu *School of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.
Zhenchao Tao *Department of Radiation Oncology, Anhui Provincial Cancer Hospital, Hefei, 230031, China.
Yu ZhangSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.
Qian ChenSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.
Zhaohua MiaoSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.
Zhengbao ZhaSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.
Yan MaSchool of Biomedical Engineering, Anhui Medical University, Hefei, 230022, China. may@ahmu.edu.cn.
Hua WangDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. wanghua@ahmu.edu.cn.
Deyan GongSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China. gongdy@hfut.edu.cn.

Funding

Distinguished Youth of Natural Science Research Projects in Anhui Province Universities 2024AH020005Fundamental Research Funds for the Central Universities JZ2025HGTB0244National Natural Science Foundation of China 82202221National Natural Science Foundation of China 82370562Natural Science Foundation of Anhui Province 2208085Y24Research Fund of Anhui Institute of Translational Medicine 2022zhyx-B02
6 · The paper itself

Abstract

The ongoing progression of acetaminophen (APAP)-induced liver injury (AILI) resulting from excessive APAP intake can lead to acute liver failure (ALF). This process involves an imbalanced antioxidant system, upregulated inflammatory responses, and excessive accumulation of reactive oxygen and nitrogen species (RONS), which ultimately trigger apoptosis. In the present study, tannic acid-capped tungsten disulfide nanosheets (WS

Indexed as

AcetaminophenChemical and Drug Induced Liver InjuryDisulfidesReactive Nitrogen SpeciesReactive Oxygen SpeciesTungstenTungsten CompoundsAnimalsAnti-Inflammatory AgentsAntioxidantsApoptosisHumansLiverMaleMiceOxidative StressAcetaminophenAnti-Inflammatory AgentsAntioxidantsDisulfidesReactive Nitrogen SpeciesReactive Oxygen SpeciesTungstenTungsten CompoundsAcute liver injuryPharmacology and toxicologyRONS scavengingTungsten disulfideTwo-dimensional nanomedicine

Identifiers

PMID41076517
PMCPMC12514798

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.