ArticleBiological trace element research2026
Trace Element Imbalances in ADHD: Hair Mineral Profiling via Synchrotron X-ray Fluorescence and Wavelength-Dispersive X-ray Fluorescence.
Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
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Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
This study examined hair mineral concentrations in children with attention-deficit/hyperactivity disorder (ADHD) compared to neurotypical controls using advanced analytical techniques. We employed synchrotron-based X-ray fluorescence (XRF) and WD-XRF to analyze hair samples from 49 ADHD-diagnosed children and 50 age-matched controls (6-18 years). Key findings revealed significant mineral imbalances in the ADHD group, including decreased levels of sulfur (S), zinc (Zn), and copper (Cu) alongside elevated aluminum (Al), bromine (Br), and chromium (Cr) concentrations (all p < 0.05). While manganese (Mn) showed no significant group difference, its trending lower levels in ADHD warrants further investigation given its neurotoxic potential. These elemental disturbances may contribute to dopaminergic dysfunction and behavioral symptoms characteristic of ADHD. The study demonstrates that hair mineral analysis serves as a valuable non-invasive tool for assessing long-term elemental exposure patterns in neurodevelopmental disorders. Our results suggest potential diagnostic utility of specific mineral profiles and highlight opportunities for targeted nutritional or environmental interventions. Further research should explore whether correcting these mineral abnormalities could ameliorate ADHD symptoms.
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Registered trials
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