ReviewOtolaryngologic clinics of North America2026
Surgically Based Deintensification for Oropharyngeal Cancer: Current Concepts and Future Directions.
Review in Otolaryngologic clinics of North America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The paradigm for management of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (HPV + OPC) has evolved significantly in recent years. Following the interim futility analysis of NRG HN005, which reaffirmed standard-dose cisplatin-based chemoradiation as the standard of care in the nonsurgical setting, this review examines whether surgical approaches now represent the most viable path to treatment deintensification for appropriate patients with HPV + OPC. In this narrative review, we summarize data from key surgical deintensification clinical trials, discuss surgeon credentialing considerations, and review emerging technologies that may further refine patient selection and treatment response assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.