Observational studyIndian heart journal
Clinical and functional outcome of fractional flow reserve guided management of triple vessel coronary artery disease.
Observational study in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFractional Flow Reserve (FFR) helps to assess the functional significance of a coronary stenosis accurately, particularly in triple vessel disease (TVD) where other modalities are ineffectual. There is dearth of data using FFR in TVD. In this study, we assessed outcome of FFR guided management in a spectrum of TVD.
methodsA prospective observational study was conducted at four tertiary care hospitals of the armed forces between Aug 2019 and Aug 2023. Patients diagnosed with intermediate TVD on coronary angiogram (CAG) were included in the study. Initial treatment strategy based on CAG was noted. Treatment was reformulated based on FFR findings. Primary end points of death, myocardial infarction, repeat revascularization and stroke were evaluated at 3, 6 and 12 months.
results145 patients were studied. 60 % presented with acute coronary syndrome (ACS). None of the mild stenosis (30-50 %) were found to be FFR positive in any of the vessels. 4.8 % lesions in LAD, 6.2 % lesions in LCx and 2.8 % lesions in RCA were found to be functionally non-significant despite having >70 % stenosis. Post FFR treatment variation was seen in 8.3 % in PCI group and surgery was averted in 33.3 % of CABG group. All-cause mortality was 3.5 %, 1.4 % had stroke and 1.4 % of patients required repeat revascularization. 83.5 % of all patients remained asymptomatic post intervention at 12 months follow-up.
conclusionsFFR guided management lead to change of plan in a substantial 15.2 % of patients when compared to CAG based management. FFR negativity in LAD was the main reason for majority of TVD patients ending up with PCI instead of CABG.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.