ArticleACS nano2025
2240 nm NIR-IV Photodynamic Therapy Can Reverse Ineffective Anti-OX40 Cancer Immunotherapy to Become Effective.
Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Recent Advances in Nanomedicine-Enhanced Photodynamic Therapy in Cutaneous Oncology: Melanoma-Dominant Evidence for Immunogenic Cell Death and Photoimmunotherapy.International journal of molecular sciences · 2026Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The discovery of immune checkpoint inhibitor (ICI) therapies was granted the Nobel Prize in 2018. However, ICI immunotherapies were later found working poorly for the large majority (70-80%) of cancer patients. It is an urgent need to develop a strategy to conquer this grand challenge and reverse otherwise ineffective immunotherapies to become effective. Herein, we propose a "Blind T cells" model to well rationalize the course leading to the ineffectiveness of immunotherapies. We demonstrate an effective strategy to conquer the ineffectiveness of immunotherapies via producing a large amount of newly generated tumor-recognizing cytolytic CD8
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Registered trials
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