Evidence map›Paper›PMID 41075153›Full record

ArticleAnnals of nuclear medicine2026

Evaluation of cumulative absorbed dose in tumors of various sizes regarding

Sepideh Shafiei, Hassan Yousefnia

Abstract read
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Article in Annals of nuclear medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sepideh ShafieiRadiation Applications Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, 14155-1339, Iran. sshafiei@aeoi.org.ir.
Hassan YousefniaRadiation Applications Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, 14155-1339, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesProducing several alpha-emitting isotopes in the decay chain of

methodsThe cumulative dose in tumors of various sizes (with radii of 0.6, 1.2, and 1.8 cm) resulting from the decay of

resultsThe cumulative dose within the tumor increases over time and is inversely proportional to the tumor's volume. The radial distribution of the cumulative dose within the tumor indicated that

conclusionsBy taking into account the size of the tumor and the required therapeutic dose, the proposed calculation method can be employed to determine the necessary injected activity and characteristics of a radiopharmaceutical. This includes identifying a suitable retention time and tumor uptake to improve therapeutic outcomes.

Indexed as

Absorption, RadiationAlpha ParticlesNeoplasmsRadiation DosageThoriumAnimalsCell Line, TumorHumansMiceRadiopharmaceuticalsRadiotherapy DosageTissue DistributionRadiopharmaceuticalsThoriumThorium-227227Th-based radiopharmaceuticalsCumulative doseMonte Carlo simulationsRadial distribution of absorbed doseTargeted alpha therapyTime dependence of absorbed dose

Identifiers

PMID41075153

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.