ArticleObesity surgery2025
Anthropometric Changes and Systemic Inflammation After Sleeve Gastrectomy: Do Composite Markers Reflect the Change?
Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study evaluated how sleeve gastrectomy affects inflammatory and nutritional markers in obese, comorbidity-free individuals, and their relationship with anthropometric measurements.
methodsThis study retrospectively evaluated 160 obese patients who underwent primary laparoscopic sleeve gastrectomy from 2021 to 2024. Demographic, anthropometric, and lab data were analyzed pre- and 6 months post-op. Changes in body mass index (BMI), waist circumference, and weight loss percentages were calculated. Hepatic steatosis was assessed by ultrasound. Complete blood count, albumin, and hemoglobin levels were also analyzed. From these, the Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score, Systemic Immune-Inflammation Index (SII), Prognostic Nutritional Index (PNI), Pan-Immune-Inflammation Value (PIV), lymphocyte-to-monocyte ratio (LMR), and Modified Systemic Inflammation Score (mSIS) were calculated.
resultsThe patients averaged 33.7 ± 10.4 years old; 61.9% (n = 99) were female. Post-op, significant decreases occurred in body weight, BMI, waist circumference, hepatic steatosis, neutrophil, lymphocyte, monocyte, and platelet counts, SII, and PIV (p < 0.001 for all, except lymphocytes, p = 0.002). LMR significantly increased (p < 0.001), while PNI showed a mild but significant decrease (p = 0.021). Although weak positive correlations were observed between the reduction in waist circumference and HALP (r = 0.171, p = 0.038), and between the percentage reduction in waist circumference and change in SII (r = 0.159, p = 0.046), no significant relationship was found between the change in the anthropometric measurements and inflammatory markers overall.
conclusionsSleeve gastrectomy significantly reduces both weight and systemic inflammation. However, there's no significant association between weight loss or body composition and inflammatory markers. This suggests that factors beyond just weight reduction may influence systemic inflammation.
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Registered trials
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