Evidence map›Paper›PMID 41075141›Full record

SynthesisWorld journal of pediatrics : WJP2026

Comprehensive exercise recommendations for pediatric asthma: an evidence synthesis.

Hong-Zhen Xu, Nan Lin, Guan-Nan Bai, Yu-Lin Liu, Xiao-Hui Jia, Cong Huang, Liang Hu, Han-Qing Shao, Qi-Yun Shang, Li-Fang Zhang and 7 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of pediatrics : WJP, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Early childhood asthma and adiposity until adolescence: A prospective birth cohort study using body fat percentage.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Hong-Zhen XuNursing Department, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China. 6184020@zju.edu.cn.ORCID 0000-0001-9962-1963
Nan LinNursing Department, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Guan-Nan BaiDepartment of Child Health Care, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China. guannanbai@zju.edu.cn.
Yu-Lin LiuDepartment of Respiratory, Children's Hospital of Chongqing Medical University, Chongqing, 401122, China.
Xiao-Hui JiaDepartment of Pediatric Respiratory Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325035, China.
Cong HuangDepartment of Sports Science, College of Education, Zhejiang University, Hangzhou, 310058, China.
Liang HuDepartment of Sports Science, College of Education, Zhejiang University, Hangzhou, 310058, China.
Han-Qing ShaoDepartment of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Qi-Yun ShangDepartment of Pediatric Respiratory Disease, Anhui Provincial Children's Hospital, Hefei, 230051, China.
Li-Fang ZhangDepartment of Respiratory and Critical Care Medicine, Kunming Children's Hospital, Kunming, 650000, China.
Ying-Shuo WangDepartment of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Yuan-Yuan ZhangDepartment of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Lan-Fang TangDepartment of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Yun-Lian ZhouDepartment of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Guo-Hong ZhuDepartment of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Jian-Guo HongDepartment of Pediatrics, Shanghai General Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. hongjianguo@hotmail.com.
Zhi-Min ChenDepartment of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China. zmchen@zju.edu.cn.

Funding

Key Research and Development Program of Zhejiang Province 2024C03177Scientific Research Fund of the Zhejiang Provincial Education Department Y202352389
6 · The paper itself

Abstract

backgroundBronchial asthma is a common chronic respiratory disease in children. For many years, concerns about exercise-induced bronchoconstriction have limited physical activity in this population, with negative consequences for both physical and mental health. Recent evidence indicates that exercise should be incorporated into the daily routine of children with asthma, with appropriately prescribed programs shown to improve disease control, lung function, and quality of life. This study aims to systematically describe the safety, benefits and key factors of exercise for children with asthma. DATA SOURCES: Initiated by the National Clinical Research Center for Child Health, this set of recommendations was developed by a multidisciplinary team of 17 experts. A comprehensive Literature search was conducted across PubMed, Embase, Cochrane and other databases, yielding 64 studies that met inclusion criteria up to May 2025. The Oxford Centre for Evidence-Based Medicine 2011 levels of evidence were used to evaluate evidence quality. Two rounds of expert voting were conducted using Delphi methodology to formulate final recommendations on key clinical topics.

resultsRecommendations were formulated across nine core domains: exercise safety, exercise-related benefits, pre-exercise screening, exercise prescription design, plan adjustment and progression, pre-exercise preparation, exercise monitoring, outcome assessment and the management of exercise-induced bronchoconstriction. Specific guidance is offered on individualized exercise planning based on asthma control status, physical fitness, exercise habits and environmental factors. Recommendations also address appropriate modalities of aerobic, resistance and flexibility training, strategies for monitoring intensity and progression and both pharmacologic and non-pharmacologic approaches to exercise-induced bronchoconstriction prevention and management.

conclusionsThese recommendations provide scientific and practical guidance for the development and implementation of individualized exercise prescriptions in children with asthma. Moreover, they highlight the importance of multidisciplinary collaboration and reinforce exercise as an integral component of asthma management. Further high-quality clinical research is needed to optimize exercise protocols and evaluate long-term outcomes.

Indexed as

AsthmaExercise TherapyChildEvidence-Based MedicineHumansAsthmaChildExerciseExercise-induced bronchoconstrictionRecommendation

Identifiers

PMID41075141
PMCPMC12923401

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.