ArticleWorld journal of pediatrics : WJP2025
Impact of COVID-19 pandemic on childhood asthma and wheezing disorders.
Article in World journal of pediatrics : WJP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Shifts in acute respiratory pathogen epidemiology: an 8-year surveillance study in Hangzhou, China (2018-2025).Frontiers in public health · 2026Article
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8 authors.
Funding
Abstract
backgroundSince the lifting of COVID-19 control measures, infections by common respiratory pathogens have emerged as a public health issue, and the impacts on vulnerable children with wheezing illnesses remain uncertain.
methodsThis prospective study enrolled children (< 18 years) hospitalized for wheezing disorders in Hong Kong (2016‒2025). Nasopharyngeal aspirates collected within 12 h of admission were tested via rapid antigen detection, viral culture, and multiplex polymerase chain reaction (PCR) for respiratory viruses. Bacterial pathogens were identified through cultures of blood/airway specimens or PCR, including Chlamydia pneumonia and mycoplasma pneumoniae detection via PCR.
resultsA total of 2499 children [66.8% male, median age 2.9 (3.6) years)] with 3272 admissions due to wheezing disorders were identified. There was a substantial reduction in pediatric wheezing admissions during the COVID-19 pandemic (February 2020 to January 2023) compared to the pre-pandemic period (September 2016 to January 2020). After removing pandemic restrictions, wheezing admissions drastically increased from February 2023 to February 2025, exceeding the pre-pandemic level. A fivefold increase was observed in admissions due to "bronchiolitis" compared with that during the pandemic period (P < 0.001). The post-pandemic proportion of respiratory syncytial virus (RSV) significantly increased, especially among those under 5 years of age (P < 0.01). Coinfections with multiple pathogens were more common during and after the pandemic than pre-pandemic (P < 0.05).
conclusionsLifting restrictions led to a resurgence of wheezing admissions and respiratory infections. Continued pathogen monitoring in the post-pandemic era is crucial, and preventive measures for future health crises are needed.
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