ArticleClinical rheumatology2025
Respiratory muscle strength in radiographic axial spondyloarthritis: clinical significance and predictors.
Article in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
INTRODUCTION/
objectiveRespiratory muscle function may be impaired in axial spondyloarthritis (axSpA) due to mechanical limitations of the thoracic spine and chest wall. However, the extent of respiratory muscle weakness and its clinical associations remain largely underexplored.
methodsThis comparative cross-sectional study included 51 patients with radiographic axSpA (r-axSpA) and 52 healthy controls. Maximal inspiratory (PI
resultsAlthough the PI
conclusionAlthough respiratory muscle strength was mostly preserved in r-axSpA, a substantial subgroup exhibited inspiratory muscle weakness associated with adverse clinical outcomes. Identifying these patients may guide tailored interventions for optimal care. KEY POINTS: A substantial proportion of patients with radiographic axSpA demonstrate inspiratory muscle weakness despite preserved average respiratory pressures. Patients with inspiratory muscle weakness exhibit diminished lung volumes, decreased spinal mobility, higher pain levels, and poorer quality of life compared to those without weakness. Inspiratory muscle strength is independently predicted by spinal pain at rest and forced vital capacity.
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