Evidence map›Paper›PMID 41075107›Full record

ReviewCurrent oncology reports2025

Management of Desmoid Tumors.

Juneko E Grilley-Olson, Gina Sotolongo, William R Jeck, Charles Y Kim, Nicole Larrier, Dan G Blazer Iii, Richard F Riedel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Percutaneous Management of Desmoid Tumors.Current oncology reports · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juneko E Grilley-OlsonDivision of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA.
Gina SotolongoDepartment of Pathology, Duke University Medical Center, Durham, NC, USA.
William R JeckDepartment of Pathology, Duke University Medical Center, Durham, NC, USA.
Charles Y KimDepartment of Radiology, Duke University Medical Center, Durham, NC, USA.
Nicole LarrierDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC, USA.
Dan G Blazer IiiDepartment of Surgery, Duke University Medical Center, Durham, NC, USA.
Richard F RiedelDivision of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA. richard.riedel@duke.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review highlights the evolving management of desmoid tumors, including the importance of an accurate diagnosis, the potential role for surgery and radiation therapy in select cases, growing data supporting the use of radiology-guided techniques, as well as the emerging role of systemic therapy for disease not amenable to active surveillance. RECENT

findingsThe initial management for desmoid tumors has shifted towards watchful waiting for a majority of patients. The recent FDA approval of nirogacestat, a gamma-secretase inhibitor, as well as prospective clinical trials examining multitargeted tyrosine kinase inhibitors, have increased systemic therapy options for patients. Local therapies, such as surgery, radiation and radiology-guided techniques, remain potential options in appropriate situations. An improved understanding of the underlying biology and inherent behavior of desmoid tumors has resulted in a rapidly evolving and shifting treating paradigm. A multi-disciplinary approach is critically important to provide the best outcomes for patients.

Indexed as

Desmoid TumorsHumansAggressive fibromatosisDesmoid tumorDiagnosisMultidisciplinary managementNovel therapiesRadiation therapyRadiology-guided techniquesSurgerySystemic therapyTyrosine kinase inhibitors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.