ArticleJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2025
Differential Effects of Cannabinoid Receptor 2 Agonists on HIV Replication and Inflammatory Activation in Monocyte-Derived Macrophages and Induced Pluripotent Stem Cell-Derived Microglia.
Article in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
6 authors.
Alexander StarrDepartment of Oral Medicine, School of Dental Medicine, University of Pennsylvania, 240 S. 40th St, Rm 312 Levy, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0002-0756-4082
Sara RathoreDepartment of Oral Medicine, School of Dental Medicine, University of Pennsylvania, 240 S. 40th St, Rm 312 Levy, Philadelphia, PA, 19104, USA.
Cagla Akay-EspinozaDepartment of Oral Medicine, School of Dental Medicine, University of Pennsylvania, 240 S. 40th St, Rm 312 Levy, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0003-0199-3836
Kelly L Jordan-SciuttoDepartment of Oral Medicine, School of Dental Medicine, University of Pennsylvania, 240 S. 40th St, Rm 312 Levy, Philadelphia, PA, 19104, USA. jordank@upenn.edu.ORCID http://orcid.org/0000-0002-0827-1337
Funding
Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI A. Clementina Mesaros · 2006 to 2026
$35.3M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Karine Dube, Kelly L Jordan-Sciutto · 2013 to 2026
$23.5M
PREDOCTORAL TRAINING PROGRAM IN PHARMACOLOGYT32GM008076 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BLENDY, JULIE A · 1985 to 2023
$10.8M
Inter- and Intra-cellular effects of cannabinoids, HIV and ART in the CNSR01DA052826 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI JORDAN-SCIUTTO, KELLY L · 2021 to 2025
$3.5M
Modeling CNS dynamics in HIV infection and cannabinoids with forebrain organoidsR01DA049514 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIAN, KIMBERLY, JORDAN-SCIUTTO, KELLY L · 2019 to 2023
$3.5M
Benzodiazepine mediated mechanisms of transcriptional semi-quiescence in discrete myeloid populationsR01DA057337 · NIDA · DREXEL UNIVERSITY · PI Peter Jesse Gaskill, Zachary Alan Klase · 2022 to 2026
$3.4M
Viral dynamics of rebound and reservoir HIV species in IPSC-derived myeloid cellsR21MH129193 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI AKAY ESPINOZA, CAGLA · 2022 to 2023
$431k
Future self: An episodic future thinking intervention for comorbid tobacco use disorder and bipolar disorderK23DA058051 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI GOLD, ALEXANDRA KATE · 2024 to 2025
$393k
Cannabinoid Modulation of Neuroinflammation in Human iPSC Models of HIV InfectionF31DA054001 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI STARR, ALEXANDER · 2021 to 2023
Emerging evidence suggests brain-resident myeloid cells, including perivascular macrophages and microglia, provide a reservoir for HIV infection in the central nervous system (CNS), and their inflammatory activation is a proposed pathogenic mechanism in HIV-associated neurocognitive disorders (HAND). We investigated whether cannabinoid receptor 2 (CB
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Differential Effects of Cannabinoid Receptor 2 Agonists on HIV Replication and Inflammatory Activation in Monocyte-Derived Macrophages and Induced Pluripotent Stem Cell-Derived Microglia. · full record | OpenQuestion