ArticleJournal of materials science. Materials in medicine2025
Calcification Potential of Intraocular Lenses (IOL). Predictive in vitro and in vivo models.
Article in Journal of materials science. Materials in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Opacification of intraocular lenses (IOLs) due to the formation of calcium phosphate occurs because of their contact with the aqueous humor (AH), which is supersaturated with respect to calcium phosphate. Calcification of IOLs was simulated in vitro using a batch reactor in which the IOLs were exposed to solutions simulating AH. Based on the precise and reproducible measurement of the rates of formation of mineral deposits on the IOLs, it is possible to develop reliable screening tests of different types of IOL materials. Depending on their material composition, IOLs are expected to present different active sites for the growth of deposits. Measurements of the kinetics of formation of hydroxyapatite (Ca
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