ArticleBioprocess and biosystems engineering2026
Carbon source-mediated metabolic and bioprocess optimization for C-phycocyanin enrichment in Phormidium sp. A02 under two-phase static mixotrophic culture.
Article in Bioprocess and biosystems engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
C-Phycocyanin (C-PC), a fluorescent photosynthetic protein derived from cyanobacteria, is used in the food, cosmetic, pharmaceutical, and biotechnology industries. Various cyanobacterial sources of C-PC have been studied to harness its biological functions such as antimicrobial, antioxidant, anticancer, and anti-inflammatory properties. Phormidium sp. A02 isolate from the Indian coast was cultured in a mixotrophic static environment to determine the effect of various bioprocess parameters like culture medium and light (photoperiod, light intensity, and light color) on biomass productivity and C-PC content. The C-PC from Phormidium sp. A02 can be used in the food and cosmetic industry as an alternative to synthetic chemical colorants. Carbon-mediated metabolic engineering of C-PC in Phormidium sp. A02 using Guillard's F/2 seawater medium supplemented with carbon sources like glucose, sucrose, glucose + peptone, and sucrose + peptone was carried out to determine its growth and C-PC enhancement efficiency. Sucrose + peptone with C/N ratio 4.76 increased Phormidium sp. A02 biomass productivity (0.197 ± 0.02 g dry weight L
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