Controlling 3-hydroxyhexanoate mole fraction in poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) by altering enoyl-CoA hydratase (phaJ) ribosome-binding site in Cupriavidus necator H16.

Yuni Shin, Gaeun Lim, Yebin Han, Jeong Chan Joo, Hee-Taek Kim, Jong-Min Jeon, Jeong-Jun Yoon, Shashi Kant Bhatia, Yung-Hun Yang

Abstract read

PubMed Publisher

In one paragraph

Article in Bioprocess and biosystems engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuni ShinAdvanced Materials Program, Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, 05029, Republic of Korea.

Gaeun LimAdvanced Materials Program, Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, 05029, Republic of Korea.

Yebin HanAdvanced Materials Program, Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, 05029, Republic of Korea.

Jeong Chan JooDepartment of Chemical Engineering, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.

Hee-Taek KimDepartment of Food Science and Technology, Chungnam National University, Daejeon, Republic of Korea.

Jong-Min JeonGreen Circulation R&D Department, Korea Institute of Industrial Technology (KITECH), Cheonan, Republic of Korea.

Jeong-Jun YoonGreen Circulation R&D Department, Korea Institute of Industrial Technology (KITECH), Cheonan, Republic of Korea.

Shashi Kant BhatiaAdvanced Materials Program, Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, 05029, Republic of Korea.

Yung-Hun YangAdvanced Materials Program, Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, 05029, Republic of Korea. seokor@konkuk.ac.kr.

Funding

National Research Foundation of Korea (NRF) NRF- 2022R1A2C2003138, NRF-2022M3I3A1082545R&D Program of the Ministry of Trade, Industry, and Energy (MOTIE)/Korea Evaluation Institute of Industrial Technology (KEIT) 20025698, 02311604 and 00467186

6 · The paper itself

Abstract

Polyhydroxyalkanoate (PHA) is a bioplastic attracting interest as an alternative to petroleum-based plastics. Particularly, poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) (P(3HB-co-3HHx)), which shows notable polymeric properties, is usually produced using the engineered Cupriavidus necator. Currently, production of P(3HB-co-3HHx) is primarily possible by engineering phaC, however, relatively rare study of controlling the expression of enoyl-CoA hydratase (phaJ

Indexed as

3-Hydroxybutyric AcidBacterial ProteinsCaproatesCupriavidus necatorEnoyl-CoA HydrataseRibosomesBinding SitesPolyhydroxybutyrates3-Hydroxybutyric AcidBacterial ProteinsCaproatesEnoyl-CoA Hydratasepoly(3-hydroxybutyrate-co-3-hydroxyhexanoate)PolyhydroxybutyratesCupriavidus necatorphaC BP-M-CPF4phaJ PaPolyhydroxyalkanoateRibosome-binding site (RBS)

Identifiers

PMID41074969

DOI10.3390/polym17131824

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.