Evidence map›Paper›PMID 41074925›Full record

ReviewJournal of materials science. Materials in medicine2025

"Advancing cardiac patch viability and functionality: innovations in scaffold design and cellular optimization".

Ahmed Eliwa, M K G Abbas, Maryam Al-Ejji

Abstract readReview
In one paragraph

Review in Journal of materials science. Materials in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmed EliwaDepartment of Basic Medical Sciences, College of Medicine, Qatar University, Doha, Qatar. ae1801741@qu.edu.qa.
M K G AbbasCenter for Advanced Materials (CAM), Qatar University, Doha, Qatar.
Maryam Al-EjjiCenter for Advanced Materials (CAM), Qatar University, Doha, Qatar.

Funding

Qatar National Research Fund 14S-0317-210064Qatar University QUST-1-CAM-2024-1745
6 · The paper itself

Abstract

Cardiac patches represent a groundbreaking approach in the treatment of heart disease, offering a new hope for patients with damaged heart tissue following a myocardial infarction (MI). These engineered patches not only provide essential structural support to weakened heart tissue but also actively promote regeneration by recreating a functional, contractile environment. However, achieving long-term success with cardiac patches requires innovative strategies to address the complexities of the cardiac environment. This review addresses the significant challenge of maintaining cell viability and functionality in the large-scale production of cardiac patches. It aims to advance the effectiveness of cardiac patches for clinical applications in treating heart diseases through various methods, including the incorporation of conductive materials and the use of biocompatible scaffold materials to mimic native cardiac tissue. Strategies to promote vascularization, optimize cell sources, and refine cell culture conditions are also discussed. Additionally, controlled release systems for growth factors, surface modification techniques, and mechanical conditioning during in vitro culture are highlighted as crucial aspects of patch fabrication.

Indexed as

Tissue EngineeringTissue ScaffoldsAnimalsBiocompatible MaterialsCell SurvivalHumansMyocardial InfarctionMyocytes, CardiacRegenerationBiocompatible Materials

Identifiers

PMID41074925
PMCPMC12515126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.