Evidence map›Paper›PMID 41074693›Full record

ArticleAllergy2026

The Nasal Microbiome and Associations With Environmental Exposures and Respiratory Health.

Javier Perez-Garcia, Anne K Bozack, Sheryl L Rifas-Shiman, Yanjiao Zhou, Joanne Sordillo, Brent Coull, Heike Luttmann-Gibson, Joel Schwartz, Marie-France Hivert, Emily Oken and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Javier Perez-GarciaDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford University, Stanford, California, USA.ORCID https://orcid.org/0000-0001-7813-4381
Anne K BozackDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford University, Stanford, California, USA.
Sheryl L Rifas-ShimanDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.
Yanjiao ZhouDepartment of Medicine, UConn School of Medicine, Farmington, Connecticut, USA.
Joanne SordilloDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.ORCID https://orcid.org/0009-0004-8702-4925
Brent CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Heike Luttmann-GibsonDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Marie-France HivertDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.
Emily OkenDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.
Diane R GoldDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Andres CardenasDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford University, Stanford, California, USA.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Prenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6M
Maintain and Enrich Resource Infrastructure for Project Viva: a pre-birth cohort with follow up into adolescenceR24ES030894 · NIEHS · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2020 to 2024
$2.0M
PRENATAL AND POSTNATAL EXPOSURE TO ENVIRONMENTAL MIXTURES: NEURODEVELOPMENT AND DNA METHYLATION BIOMARKERSR01ES031259 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI CARDENAS, ANDRES · 2020 to 2024
$1.9M
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES031259NIH HHSUnited States National Institutes of Health (NIH) P30-ES000002United States National Institutes of Health (NIH) R01ES031259United States National Institutes of Health (NIH) R01HD034568United States National Institutes of Health (NIH) R24ES030894
6 · The paper itself

Abstract

backgroundThe nasal microbiome is directly in contact with the external environment and may play a role in respiratory health. This study aimed to evaluate the association of the nasal microbiome with air pollutants, meteorological conditions, and respiratory health in adolescents.

methodsWe analyzed the nasal microbiome in 416 adolescents from the Project Viva cohort (mean age 13 years and 52% female). We tested for the association of alpha diversity, nasotypes, and bacterial genera abundance with environmental exposures from the past 2 days to the past year (PM

resultsBacterial diversity was positively associated with hay fever and short-term exposure to NO

conclusionsNasal microbiome diversity was associated with hay fever, NO

Indexed as

Environmental ExposureMicrobiotaRespiratory Tract DiseasesAdolescentAir PollutantsBacteriaFemaleHumansMaleAir Pollutantsair pollutantsallergy and immunologyenvironmental healthmicrobiomepediatrics

Identifiers

PMID41074693
PMCPMC12954560

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.