Evidence map›Paper›PMID 41074669›Full record

SynthesisNursing in critical care2025

The Effects of Family Voice Intervention on Delirium in Adult Critical Care Patients: A Systematic Review and Meta-Analysis.

Junhee Lee, Jiyeon Kang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Nursing in critical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Junhee LeeNeurological Intensive Care Unit, Dong-A University Hospital, Busan, South Korea.ORCID https://orcid.org/0009-0000-4268-7849
Jiyeon KangCollege of Nursing, Dong-A University, Busan, South Korea.ORCID https://orcid.org/0000-0002-8938-7656

Funding

National Research Foundation of Korea NRF-2022R1A2C1011917
6 · The paper itself

Abstract

backgroundFamily voice interventions have emerged as a non-pharmacological approach for delirium prevention; however, evidence regarding their effectiveness remains inconsistent.

aimThe aim of this study was to evaluate the effectiveness of family voice interventions in reducing delirium among adult intensive care unit (ICU) patients. STUDY

designWe conducted a systematic review and meta-analysis. A comprehensive literature search was conducted across PubMed, EMBASE, CINAHL and the Cochrane Library from inception through 4 March 2025. Study quality was assessed using the Cochrane Risk of Bias II tool, with analyses performed using Comprehensive Meta-Analysis version 4.0.

resultsSix randomised controlled trials (reported across seven publications) involving 598 adult ICU patients were included. Family voice interventions significantly reduced delirium incidence (OR = 0.282, 95% CI: 0.126-0.630, p = 0.002) and duration (Hedges' g = -1.929, 95% CI: -2.980 to -0.879, p < 0.001). No significant effects were observed for mechanical ventilation duration (Hedges' g = -0.826, 95% CI: -1.696 to 0.044, p = 0.063) or ICU length of stay (Hedges' g = -0.534, 95% CI: -1.371 to 0.303, p = 0.211). Subgroup analysis showed multicomponent interventions significantly reduced both delirium incidence (OR = 0.178, 95% CI: 0.046-0.681, p = 0.012) and duration (Hedges' g = -1.888, 95% CI: -2.917 to -0.859, p < 0.001), while single-component interventions showed no significant effects.

conclusionsFamily voice interventions effectively reduce delirium incidence and duration in adult ICU patients, with multicomponent approaches demonstrating superior efficacy. RELEVANCE TO CLINICAL PRACTICE: Critical care nurses may incorporate family voice interventions as a practical alternative within delirium prevention strategies. Although direct family presence is generally regarded as the preferred form of engagement, recorded voice messages can provide a feasible and meaningful option to enhance patient orientation and emotional connection when families cannot always be present. PROTOCOL REGISTRATION: The study protocol was prospectively registered in the International Prospective Register of Systematic Reviews (PROSPERO: CRD42025628074).

Indexed as

Critical CareDeliriumFamilyAdultHumansIntensive Care UnitsRandomized Controlled Trials as Topicdeliriumfamilyintensive care unitsmeta‐analysissystematic review

Identifiers

PMID41074669
PMCPMC12514747

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.