Evidence map›Paper›PMID 41074664›Full record

ArticleJournal of fish diseases2026

First Detection of Lactococcus formosensis subsp. formosensis in Rainbow Trout (Oncorhynchus mykiss) in Europe.

Silvia Colussi, Giuseppe Esposito, Khalid Shahin, Pier Luigi Acutis, Lucio Fariano, Claudio Ghittino, Maria Goria, Fabio Bondavalli, Paolo Ajmone Marsan, Giorgia Bignami and 3 more

Abstract read
In one paragraph

Article in Journal of fish diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Comparative Molecular and Antimicrobial Analysis ofAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Silvia ColussiIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.ORCID https://orcid.org/0000-0002-3261-4539
Giuseppe EspositoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.ORCID https://orcid.org/0000-0001-6665-2712
Khalid ShahinPHARMAQ Analytiq UK Ltd, Inverness, UK.
Pier Luigi AcutisIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.
Lucio FarianoAzienda Agricola Canali Cavour, Regione Sagnassi, Turin, Italy.
Claudio GhittinoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.
Maria GoriaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.
Fabio BondavalliIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.
Paolo Ajmone MarsanFacoltà di Scienze Agrarie, Alimentari e Ambientali/DIANA Dipartimento di Scienze Animali, Della Nutrizione e Degli Alimenti, Università Cattolica del Sacro Cuore, Piacenza, Italy.
Giorgia BignamiDipartimento di Scienze Mediche Veterinarie, ALMA MATER STUDIORUM - Università di Bologna, Bologna, Italy.
Elena BozzettaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.
Marino PrearoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.
Paolo PastorinoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Turin, Italy.

Funding

Italian Ministry of Agriculture, Food Sovereignty and Forests RESILTROUT-6CFP code 23E03
6 · The paper itself

Abstract

Lactococcus garvieae, Lactococcus petauri and Lactococcus formosensis are etiological agents of piscine lactococcosis, a disease reported in Italy since the early 1990s and linked to significant aquaculture losses. To the best of our knowledge, this study reports the first detection of L. formosensis subsp. formosensis in farmed rainbow trout (Oncorhynchus mykiss) in Europe. In 2024, a total of 70 trout were sampled in the Piedmont region (Northern Italy), as part of a health monitoring programme. Bacteriological and molecular analyses showed the presence of L. garvieae in four fish (5.7%) and the identification of L. formosensis subsp. formosensis in one single fish exhibiting mild clinical signs via 16S-23S rRNA ITS sequencing. Phylogenetic analysis confirmed the clustering of the isolate within the L. formosensis clade, clearly distinct from L. garvieae and L. petauri. Virulotype comparison showed greater similarity between L. petauri and L. formosensis subsp. formosensis, while the latter exhibited a distinct biochemical profile and was highly susceptible to antibiotics commonly used in aquaculture. Nevertheless, monitoring and advanced diagnostics are essential to clarify the role of this bacterium and to develop any necessary preventive and control measures.

Indexed as

Fish DiseasesGram-Positive Bacterial InfectionsLactococcusOncorhynchus mykissAnimalsAquacultureItalyPhylogenyaquatic microbiologybacterial pathogenfish healthfreshwater fishpiscine lactococcosis

Identifiers

PMID41074664
PMCPMC12961731

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.