ArticleRevista de neurologia2025
Computed Tomography Perfusion Imaging: A Key Initial Test for Isolated Acute Aphasia in the Emergency Department.
Article in Revista de neurologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundComputed tomography perfusion (CTP) is a widely available imaging test in the initial assessment of acute neurological symptoms. Acute isolated aphasia is a common symptom in this group of patients, in whom an etiopathogenic diagnosis can be challenging. The aim of this study was to assess the usefulness of CTP for the initial management of this syndrome, and to evaluate whether the detection of certain perfusion patterns can be valuable in the diagnostic process.
methodsCTP scans performed in our hospital between 2019 and 2022 were retrospectively analyzed. Individuals with acute isolated aphasia who attended the emergency department within this period were included. Diagnostic, demographic, clinical, neuroimaging, electroencephalography (EEG), other complementary test, and follow-up data were collected.
resultsOf the 1880 CTP exams performed, 175 (9.3%) patients presented with acute isolated aphasia, 50% of whom were female, with a median age of 71.5 (Interquartile range (IQR) 61-80) years. The etiology was vascular in 91 (52%) patients, epileptic in 26 (14.9%) patients, and due to other causes in 58 (33.1%) patients. Differences in perfusion patterns were detected between the different etiologies (
conclusionsCTP imaging is a valuable diagnostic tool for acute isolated aphasia, enabling the optimization of acute treatment in these patients, particularly in status epilepticus and stroke.
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